This Publication Perspective provides a summary of the article ‘Afatinib for the Treatment of Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations: A Database of 693 Cases’ by James Chih-Hsin Yang and co-authors. The paper, originally published in the Journal of Thoracic Oncology, comprehensively analysed the effect of afatinib treatment in 693 patients with non-small cell lung cancer harboring uncommon EGFR mutations. The results provide important information when considering optimal treatment for tumors with uncommon EGFR mutations, including compound mutations.
Afatinib for the treatment of NSCLC harboring uncommon EGFR mutations: A database of 693 cases
James Chih-Hsin Yang, Martin Schuler, Sanjay Popat, Satoru Miura, Simon Heeke, Keunchil Park, Angela Märten & Edward S Kim
Journal of Thoracic Oncology 15(5), 803-815 (2020) DOI: 10.1016/j.jtho.2019.12.126